Doctoral Researcher/PhD

The position is offered for a period of 3 years, if no former times of qualification must be considered. The starting date is 1st August 2025. The position is part-time (50 % of regular working hours) with salary and benefits commensurate with a public service position in the state Hesse, Germany (TV-H E 13, 50 %).

The Graumann research group investigates how dynamic processes in bacterial cells are organized spatially and temporally - with a particular focus on the model organism Bacillus subtilis. The current project focuses on the molecular regulation of central metabolic pathways through direct enzyme-enzyme interactions. These mechanisms are not only fundamental for understanding bacterial cell biology, but are also highly relevant for medical issues, for example in the context of antibiotic resistance or the targeted influencing of microbial metabolic pathways. Using the latest high-resolution fluorescence microscopy and automated image analysis, substrate-dependent, dynamic complex formation at the single-molecule level in living cells is investigated - a technology platform that is increasingly being used in biomedical research.

Tasks:

• scientific services in research and teaching
• development of an original research project with high independance
• investigation of the dynamics of enzymes at the single molecule level in living Bacillus subtilis cells using single molecule tracking (SMT) fluorescence microscopy
• application and, if possible, further development of methods for automated image recognition and evaluation
• characterization of the interaction of enzymes in vivo and in vitro multidisciplinary collaboration in an international environment
• international communication in research by publications and participation in conferences
• opportunity for aiding in student courses and teaching in seminars for students

The position is limited to a time period deemed adequate for the completion of a doctoral degree. As part of the assigned duties, there will be ample opportunity to conduct the independent scientific research necessary for the completion of a doctorate. The limitation complies to § 2, 1 WissZeitVG.

Profile:

• MSc-degree or equivalent in biologiy, biochemistry or chemistry, with a focus on biochemistry and/or microbiology
• experience in dealing with different microorganisms
• ability to carry out molecular biological (cloning) and biochemical experiments (protein purfication)
• independent, autonomous thinking
• experience with cell biological techniques (e. g. super resolution fluorescence microscopy)
• ideally knowledge on or interest in computer programming (e. g. MATLAB, Python, or others)
• motivated and passionate team player

Disposition to own scientific qualification (e. g. a doctorate project in the area of biochemistry/microbiology with a focus on cell biology) is expected.

We actively support the professional development of junior researchers by the possibility to participate in the graduate program International Max Planck Research School IMPRS-Mic and the Center for Synthetic Microbiology (SYNMIKRO) and by the offers of Marburg Research Academy (MARA), the International Office and the Higher Education Didactics Office.

We offer:

• an interesting and broad range of work
• flexible working hours and part-time employment
• ticket for free use of public transport in the state Hesse, Germany
• options for remote work
• company pension scheme (VBL)

We support women and strongly encourage them to apply. In areas where women are underrepresented, female applicants will be preferred in case of equal qualifications. As a certified family-friendly university, we support our employees in balancing family and career. A reduction of working time is possible. Applicants with a disability as discribed in SGB IX (§ 2 Abs. 2, 3) will be preferred in case of equal qualifications. Application and interview costs can not be refunded.

Please apply by 6th July 2025 using the application-button below.