registration number: fb20-0018-wmz-2025

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Entry date:
as soon as possible

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Application deadline:
2025-03-02

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Salary:
E 13 TV-H

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Duration:
3 years

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Volume of employment:
part-time (65 %)

The University of Marburg, founded in 1527, offers a variety of excellent programs of study for around 22,000 students and confronts the important topics of our time through excellent research across a broad spectrum of sciences.

The Department of Medicine, Faculty of Systems Immunology, research group of Prof. Dr. Magdalena Huber, is currently accepting applications for a

Doctoral Researcher/PhD

The position is offered for a period of 3 years, if no former times of qualification must be considered. The starting date is as soon as possible. The position is part-time (65 % of regular working hours) with salary and benefits commensurate with a public service position in the state Hesse, Germany (TV-H E 13, 65 %).

This fully-funded Ph.D. position by the LOEWE-Schwerpunkt CARISMa aims to explore how the human microbiome influences cancer biology and immunotherapy, focusing on CAR T cell technology.

Tasks:

  • scientific services in research and teaching
  • CAR T cell manufacture (mouse and human) and in vitro analyses (proliferation, cytokine production, killing)
  • deletion or inhibiton of genes in CAR T cells (using different methods)
  • analyses of the effectiveness (efficacy) of CAR T cells in vivo in pancreatic mouse models and Analyses of CAR T cells from patient material
  • collaboration with a multidisciplinary team in the CARISMa consortium (experts in CAR T cell engineering, oncology and immunotherapy), assistance in questions related to CAR T cells
  • presenting findings at international conferences and publishing results in peer-reviewed journals

The position is limited to a time period deemed adequate for the completion of a doctoral degree. As part of the assigned duties, there will be ample opportunity to conduct the independent scientific research necessary for the completion of a doctorate. The limitation complies to § 2, 1 WissZeitVG.

Profile:

  • MSc-degree or equivalent in cancer biology, molecular biology/medicine, biochemistry or a related field
  • solid experience in T cell Immunology and CAR T cell methodology
  • sound experience in flow cytometry (FACS), transcriptome analyses, work with cell cultures and microscopy of T cells
  • experience in animal experiments (FELASA certification desirable)
  • experience in up-to-date methods used in molecular biology (qPCR, molecular cloning)

Disposition to own scientific qualification is expected.

We actively support the professional development of junior researchers by the offers of Marburg Research Academy (MARA), the International Office and the Higher Education Didactics Office.

We offer:

  • a dynamic and broad research environment with access to state-of-the-art facilities
  • mentorship and training opportunities in immunological analysis using preclinical models and patient-derived materials
  • an inspiring research environment with institutional research seminars and invited speaker lectures
  • participation in national and international conferences
  • opportunities for networking and collaboration with research consortia

Contact for more Information

Head of Institute: Prof. Dr. Magdalena Huber
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+49 6421-28 66818

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magdalena.huber@staff.uni-marburg.de

We support women and strongly encourage them to apply. In areas where women are underrepresented, female applicants will be preferred in case of equal qualifications. As a certified family-friendly university, we support our employees in balancing family and career. A reduction of working time is possible. Applicants with a disability as discribed in SGB IX (§ 2 Abs. 2, 3) will be preferred in case of equal qualifications. Application and interview costs can not be refunded.

Please apply by 02.03.2025 using the application-button below.

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